Title |
Feasibility and safety of robot-assisted thoracic surgery for lung lobectomy in patients with non-small cell lung cancer: a systematic review and meta-analysis
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Published in |
World Journal of Surgical Oncology, May 2017
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DOI | 10.1186/s12957-017-1168-6 |
Pubmed ID | |
Authors |
Shiyou Wei, Minghao Chen, Nan Chen, Lunxu Liu |
Abstract |
The aim of this study is to evaluate the feasibility and safety of robot-assisted thoracic surgery (RATS) lobectomy versus video-assisted thoracic surgery (VATS) for lobectomy in patients with non-small cell lung cancer (NSCLC). An electronic search of six electronic databases was performed to identify relevant comparative studies. Meta-analysis was performed by pooling the results of reported incidence of overall morbidity, mortality, prolonged air leak, arrhythmia, and pneumonia between RATS and VATS lobectomy. Subgroup analysis was also conducted based on matched and unmatched cohort studies, if possible. Relative risks (RR) with their 95% confidence intervals (CI) were calculated by means of Revman version 5.3. Twelve retrospective cohort studies were included, with a total of 60,959 patients. RATS lobectomy significantly reduced the mortality rate when compared with VATS lobectomy (RR = 0.54, 95% CI 0.38-0.77; P = 0.0006), but this was not consistent with the pooled result of six matched studies (RR = 0.12, 95% CI 0.01-1.07; P = 0.06). There was no significant difference in morbidity between the two approaches (RR = 0.97, 95% CI 0.85-1.12; P = 0.70). RATS lobectomy is a feasible and safe technique and can achieve an equivalent short-term surgical efficacy when compared with VATS, but its cost effectiveness also should be taken into consideration. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 88 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 13 | 15% |
Student > Master | 11 | 13% |
Researcher | 8 | 9% |
Other | 7 | 8% |
Unspecified | 7 | 8% |
Other | 17 | 19% |
Unknown | 25 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 38 | 43% |
Unspecified | 7 | 8% |
Biochemistry, Genetics and Molecular Biology | 3 | 3% |
Nursing and Health Professions | 2 | 2% |
Economics, Econometrics and Finance | 2 | 2% |
Other | 4 | 5% |
Unknown | 32 | 36% |