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Improving clinical trial efficiency by biomarker-guided patient selection

Overview of attention for article published in Trials, April 2014
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Title
Improving clinical trial efficiency by biomarker-guided patient selection
Published in
Trials, April 2014
DOI 10.1186/1745-6215-15-103
Pubmed ID
Authors

Ruud Boessen, Hiddo J Lambers Heerspink, Dick De Zeeuw, Diederick E Grobbee, Rolf HH Groenwold, Kit CB Roes

Abstract

In many therapeutic areas, individual patient markers have been identified that are associated with differential treatment response. These markers include both baseline characteristics, as well as short-term changes following treatment. Using such predictive markers to select subjects for inclusion in randomized clinical trials could potentially result in more targeted studies and reduce the number of subjects to recruit.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 5%
Unknown 36 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 26%
Student > Ph. D. Student 6 16%
Student > Bachelor 4 11%
Student > Master 3 8%
Other 3 8%
Other 7 18%
Unknown 5 13%
Readers by discipline Count As %
Medicine and Dentistry 12 32%
Agricultural and Biological Sciences 5 13%
Psychology 2 5%
Biochemistry, Genetics and Molecular Biology 2 5%
Engineering 2 5%
Other 8 21%
Unknown 7 18%