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Mendeley readers
Attention Score in Context
| Title |
MATCHER: manifold alignment reveals correspondence between single cell transcriptome and epigenome dynamics
|
|---|---|
| Published in |
Genome Biology, July 2017
|
| DOI | 10.1186/s13059-017-1269-0 |
| Pubmed ID | |
| Authors |
Joshua D. Welch, Alexander J. Hartemink, Jan F. Prins |
| Abstract |
Single cell experimental techniques reveal transcriptomic and epigenetic heterogeneity among cells, but how these are related is unclear. We present MATCHER, an approach for integrating multiple types of single cell measurements. MATCHER uses manifold alignment to infer single cell multi-omic profiles from transcriptomic and epigenetic measurements performed on different cells of the same type. Using scM&T-seq and sc-GEM data, we confirm that MATCHER accurately predicts true single cell correlations between DNA methylation and gene expression without using known cell correspondences. MATCHER also reveals new insights into the dynamic interplay between the transcriptome and epigenome in single embryonic stem cells and induced pluripotent stem cells. |
X Demographics
The data shown below were collected from the profiles of 34 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 11 | 32% |
| United Kingdom | 4 | 12% |
| Germany | 2 | 6% |
| Australia | 2 | 6% |
| Spain | 1 | 3% |
| Japan | 1 | 3% |
| Unknown | 13 | 38% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 17 | 50% |
| Members of the public | 13 | 38% |
| Science communicators (journalists, bloggers, editors) | 3 | 9% |
| Practitioners (doctors, other healthcare professionals) | 1 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 221 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 221 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 67 | 30% |
| Researcher | 27 | 12% |
| Student > Master | 20 | 9% |
| Student > Bachelor | 19 | 9% |
| Professor > Associate Professor | 9 | 4% |
| Other | 30 | 14% |
| Unknown | 49 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 52 | 24% |
| Agricultural and Biological Sciences | 43 | 19% |
| Computer Science | 32 | 14% |
| Engineering | 8 | 4% |
| Neuroscience | 5 | 2% |
| Other | 23 | 10% |
| Unknown | 58 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 25. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 October 2021.
All research outputs
#1,531,790
of 25,382,440 outputs
Outputs from Genome Biology
#1,241
of 4,468 outputs
Outputs of similar age
#29,717
of 326,540 outputs
Outputs of similar age from Genome Biology
#24
of 62 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,468 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one has gotten more attention than average, scoring higher than 72% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 326,540 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 62 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.