Title |
Mechanics rules cell biology
|
---|---|
Published in |
BMC Sports Science, Medicine and Rehabilitation, July 2010
|
DOI | 10.1186/1758-2555-2-16 |
Pubmed ID | |
Authors |
James HC Wang, Bin Li |
Abstract |
Cells in the musculoskeletal system are subjected to various mechanical forces in vivo. Years of research have shown that these mechanical forces, including tension and compression, greatly influence various cellular functions such as gene expression, cell proliferation and differentiation, and secretion of matrix proteins. Cells also use mechanotransduction mechanisms to convert mechanical signals into a cascade of cellular and molecular events. This mini-review provides an overview of cell mechanobiology to highlight the notion that mechanics, mainly in the form of mechanical forces, dictates cell behaviors in terms of both cellular mechanobiological responses and mechanotransduction. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 14% |
Italy | 1 | 7% |
Finland | 1 | 7% |
Ireland | 1 | 7% |
Unknown | 9 | 64% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 11 | 79% |
Scientists | 2 | 14% |
Practitioners (doctors, other healthcare professionals) | 1 | 7% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 1 | <1% |
Netherlands | 1 | <1% |
Australia | 1 | <1% |
India | 1 | <1% |
United Kingdom | 1 | <1% |
United States | 1 | <1% |
Unknown | 128 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 30 | 22% |
Student > Ph. D. Student | 25 | 19% |
Researcher | 17 | 13% |
Student > Bachelor | 10 | 7% |
Other | 8 | 6% |
Other | 23 | 17% |
Unknown | 21 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 29 | 22% |
Engineering | 25 | 19% |
Biochemistry, Genetics and Molecular Biology | 13 | 10% |
Medicine and Dentistry | 12 | 9% |
Physics and Astronomy | 7 | 5% |
Other | 26 | 19% |
Unknown | 22 | 16% |