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Repression of human activation induced cytidine deaminase by miR-93 and miR-155

Overview of attention for article published in BMC Cancer, August 2011
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1 X user

Citations

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75 Mendeley
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Title
Repression of human activation induced cytidine deaminase by miR-93 and miR-155
Published in
BMC Cancer, August 2011
DOI 10.1186/1471-2407-11-347
Pubmed ID
Authors

Glen M Borchert, Nathaniel W Holton, Erik D Larson

Abstract

Activation Induced cytidine Deaminase (AID) targets the immunoglobulin genes of activated B cells, where it converts cytidine to uracil to induce mutagenesis and recombination. While essential for immunoglobulin gene diversification, AID misregulation can result in genomic instability and oncogenic transformation. This is classically illustrated in Burkitt's lymphoma, which is characterized by AID-induced mutation and reciprocal translocation of the c-MYC oncogene with the IgH loci. Originally thought to be B cell-specific, AID now appears to be misexpressed in several epithelial cancers, raising the specter that AID may also participate in non-B cell carcinogenesis.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 75 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 4%
United Kingdom 1 1%
China 1 1%
Canada 1 1%
Unknown 69 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 19 25%
Researcher 9 12%
Student > Master 8 11%
Student > Doctoral Student 6 8%
Student > Bachelor 6 8%
Other 11 15%
Unknown 16 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 26 35%
Biochemistry, Genetics and Molecular Biology 16 21%
Medicine and Dentistry 7 9%
Immunology and Microbiology 4 5%
Engineering 2 3%
Other 2 3%
Unknown 18 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 August 2011.
All research outputs
#18,810,584
of 23,312,088 outputs
Outputs from BMC Cancer
#5,522
of 8,441 outputs
Outputs of similar age
#101,168
of 122,005 outputs
Outputs of similar age from BMC Cancer
#56
of 105 outputs
Altmetric has tracked 23,312,088 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,441 research outputs from this source. They receive a mean Attention Score of 4.4. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 122,005 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 7th percentile – i.e., 7% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 105 others from the same source and published within six weeks on either side of this one. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.