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Repression of human activation induced cytidine deaminase by miR-93 and miR-155

Overview of attention for article published in BMC Cancer, August 2011
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1 tweeter

Citations

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33 Dimensions

Readers on

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62 Mendeley
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Title
Repression of human activation induced cytidine deaminase by miR-93 and miR-155
Published in
BMC Cancer, August 2011
DOI 10.1186/1471-2407-11-347
Pubmed ID
Authors

Glen M Borchert, Nathaniel W Holton, Erik D Larson

Abstract

Activation Induced cytidine Deaminase (AID) targets the immunoglobulin genes of activated B cells, where it converts cytidine to uracil to induce mutagenesis and recombination. While essential for immunoglobulin gene diversification, AID misregulation can result in genomic instability and oncogenic transformation. This is classically illustrated in Burkitt's lymphoma, which is characterized by AID-induced mutation and reciprocal translocation of the c-MYC oncogene with the IgH loci. Originally thought to be B cell-specific, AID now appears to be misexpressed in several epithelial cancers, raising the specter that AID may also participate in non-B cell carcinogenesis.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 62 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 5%
United Kingdom 1 2%
China 1 2%
Canada 1 2%
Unknown 56 90%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 17 27%
Researcher 9 15%
Student > Master 8 13%
Student > Doctoral Student 5 8%
Student > Bachelor 5 8%
Other 8 13%
Unknown 10 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 26 42%
Biochemistry, Genetics and Molecular Biology 14 23%
Medicine and Dentistry 6 10%
Immunology and Microbiology 3 5%
Computer Science 1 2%
Other 0 0%
Unknown 12 19%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 August 2011.
All research outputs
#9,905,804
of 12,372,945 outputs
Outputs from BMC Cancer
#3,021
of 4,558 outputs
Outputs of similar age
#67,917
of 86,474 outputs
Outputs of similar age from BMC Cancer
#15
of 24 outputs
Altmetric has tracked 12,372,945 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,558 research outputs from this source. They receive a mean Attention Score of 3.9. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 86,474 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one is in the 29th percentile – i.e., 29% of its contemporaries scored the same or lower than it.