Title |
Stringent DDI-based Prediction of H. sapiens-M. tuberculosis H37Rv Protein-Protein Interactions
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Published in |
BMC Systems Biology, December 2013
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DOI | 10.1186/1752-0509-7-s6-s6 |
Pubmed ID | |
Authors |
Hufeng Zhou, Javad Rezaei, Willy Hugo, Shangzhi Gao, Jingjing Jin, Mengyuan Fan, Chern-Han Yong, Michal Wozniak, Limsoon Wong |
Abstract |
H. sapiens-M. tuberculosis H37Rv protein-protein interaction (PPI) data are very important information to illuminate the infection mechanism of M. tuberculosis H37Rv. But current H. sapiens-M. tuberculosis H37Rv PPI data are very scarce. This seriously limits the study of the interaction between this important pathogen and its host H. sapiens. Computational prediction of H. sapiens-M. tuberculosis H37Rv PPIs is an important strategy to fill in the gap. Domain-domain interaction (DDI) based prediction is one of the frequently used computational approaches in predicting both intra-species and inter-species PPIs. However, the performance of DDI-based host-pathogen PPI prediction has been rather limited. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 2 | 7% |
France | 1 | 3% |
Unknown | 26 | 90% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 7 | 24% |
Professor > Associate Professor | 4 | 14% |
Other | 2 | 7% |
Student > Ph. D. Student | 2 | 7% |
Student > Bachelor | 2 | 7% |
Other | 3 | 10% |
Unknown | 9 | 31% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 8 | 28% |
Computer Science | 4 | 14% |
Biochemistry, Genetics and Molecular Biology | 3 | 10% |
Environmental Science | 1 | 3% |
Social Sciences | 1 | 3% |
Other | 1 | 3% |
Unknown | 11 | 38% |