Title |
Randomized controlled trial to evaluate the effects of combined progressive exercise on metabolic syndrome in breast cancer survivors: rationale, design, and methods
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Published in |
BMC Cancer, April 2014
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DOI | 10.1186/1471-2407-14-238 |
Pubmed ID | |
Authors |
Christina M Dieli-Conwright, Joanne E Mortimer, E Todd Schroeder, Kerry Courneya, Wendy Demark-Wahnefried, Thomas A Buchanan, Debu Tripathy, Leslie Bernstein |
Abstract |
Metabolic syndrome (MetS) is increasingly present in breast cancer survivors, possibly worsened by cancer-related treatments, such as chemotherapy. MetS greatly increases risk of cardiovascular disease and diabetes, co-morbidities that could impair the survivorship experience, and possibly lead to cancer recurrence. Exercise has been shown to positively influence quality of life (QOL), physical function, muscular strength and endurance, reduce fatigue, and improve emotional well-being; however, the impact on MetS components (visceral adiposity, hyperglycemia, low serum high-density lipoprotein cholesterol, hypertriglyceridemia, and hypertension) remains largely unknown. In this trial, we aim to assess the effects of combined (aerobic and resistance) exercise on components of MetS, as well as on physical fitness and QOL, in breast cancer survivors soon after completing cancer-related treatments. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 3 | 75% |
Unknown | 1 | 25% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 75% |
Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 1 | <1% |
Denmark | 1 | <1% |
Canada | 1 | <1% |
Unknown | 454 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 85 | 19% |
Student > Bachelor | 62 | 14% |
Student > Ph. D. Student | 45 | 10% |
Researcher | 38 | 8% |
Student > Postgraduate | 24 | 5% |
Other | 65 | 14% |
Unknown | 138 | 30% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 92 | 20% |
Nursing and Health Professions | 74 | 16% |
Sports and Recreations | 64 | 14% |
Psychology | 19 | 4% |
Agricultural and Biological Sciences | 16 | 4% |
Other | 40 | 9% |
Unknown | 152 | 33% |