Title |
Impact of age of first exposure to Plasmodium falciparum on antibody responses to malaria in children: a randomized, controlled trial in Mozambique
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Published in |
Malaria Journal, March 2014
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DOI | 10.1186/1475-2875-13-121 |
Pubmed ID | |
Authors |
Augusto J Nhabomba, Caterina Guinovart, Alfons Jiménez, Maria N Manaca, Llorenç Quintó, Pau Cisteró, Ruth Aguilar, Arnoldo Barbosa, Mauricio H Rodríguez, Quique Bassat, John J Aponte, Alfredo Mayor, Chetan E Chitnis, Pedro L Alonso, Carlota Dobaño |
Abstract |
The impact of the age of first Plasmodium falciparum infection on the rate of acquisition of immunity to malaria and on the immune correlates of protection has proven difficult to elucidate. A randomized, double-blind, placebo-controlled trial using monthly chemoprophylaxis with sulphadoxine-pyrimethamine plus artesunate was conducted to modify the age of first P. falciparum erythrocytic exposure in infancy and assess antibodies and malaria risk over two years. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | <1% |
Spain | 1 | <1% |
United States | 1 | <1% |
Unknown | 115 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 16 | 14% |
Researcher | 15 | 13% |
Student > Bachelor | 15 | 13% |
Student > Master | 14 | 12% |
Student > Doctoral Student | 8 | 7% |
Other | 18 | 15% |
Unknown | 32 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 23 | 19% |
Agricultural and Biological Sciences | 19 | 16% |
Biochemistry, Genetics and Molecular Biology | 10 | 8% |
Immunology and Microbiology | 9 | 8% |
Nursing and Health Professions | 6 | 5% |
Other | 13 | 11% |
Unknown | 38 | 32% |