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Attention Score in Context
Title |
Oligomer-targeting with a conformational antibody fragment promotes toxicity in Aβ-expressing flies
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Published in |
Acta Neuropathologica Communications, April 2014
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DOI | 10.1186/2051-5960-2-43 |
Pubmed ID | |
Authors |
Jessica Wacker, Raik Rönicke, Martin Westermann, Melanie Wulff, Klaus G Reymann, Christopher M Dobson, Uwe Horn, Damian C Crowther, Leila M Luheshi, Marcus Fändrich |
Abstract |
The self-assembly of Aβ peptides into a range of conformationally heterogeneous amyloid states represents a fundamental event in Alzheimer's disease. Within these structures oligomeric intermediates are considered to be particularly pathogenic. To test this hypothesis we have used a conformational targeting approach where particular conformational states, such as oligomers or fibrils, are recognized in vivo by state-specific antibody fragments. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Italy | 1 | 3% |
Germany | 1 | 3% |
Unknown | 35 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 9 | 24% |
Student > Ph. D. Student | 7 | 19% |
Student > Bachelor | 3 | 8% |
Student > Master | 3 | 8% |
Professor > Associate Professor | 2 | 5% |
Other | 5 | 14% |
Unknown | 8 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 9 | 24% |
Biochemistry, Genetics and Molecular Biology | 7 | 19% |
Medicine and Dentistry | 3 | 8% |
Neuroscience | 3 | 8% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
Other | 4 | 11% |
Unknown | 10 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 April 2014.
All research outputs
#20,941,392
of 23,577,654 outputs
Outputs from Acta Neuropathologica Communications
#1,360
of 1,436 outputs
Outputs of similar age
#195,545
of 228,584 outputs
Outputs of similar age from Acta Neuropathologica Communications
#22
of 23 outputs
Altmetric has tracked 23,577,654 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,436 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.9. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 228,584 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.