Title |
Association study in siblings and case-controls of serotonin- and oxytocin-related genes with high functioning autism
|
---|---|
Published in |
Journal of Molecular Psychiatry, January 2014
|
DOI | 10.1186/2049-9256-2-1 |
Pubmed ID | |
Authors |
Johanna Nyffeler, Susanne Walitza, Elise Bobrowski, Ronnie Gundelfinger, Edna Grünblatt |
Abstract |
Autism spectrum disorder (ASD) is heritable and neurodevelopmental with unknown causes. The serotonergic and oxytocinergic systems are of interest in autism for several reasons: (i) Both systems are implicated in social behavior, and abnormal levels of serotonin and oxytocin have been found in people with ASD; (ii) treatment with selective serotonin reuptake inhibitors and oxytocin can yield improvements; and (iii) previous association studies have linked the serotonin transporter (SERT; SLC6A4), serotonin receptor 2A (HTR2A), and oxytocin receptor (OXTR) genes with ASD. We examined their association with high functioning autism (HFA) including siblings and their interaction. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Croatia | 1 | 1% |
Chile | 1 | 1% |
Denmark | 1 | 1% |
Unknown | 74 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 15 | 19% |
Student > Master | 15 | 19% |
Student > Bachelor | 11 | 14% |
Student > Ph. D. Student | 9 | 12% |
Student > Doctoral Student | 5 | 6% |
Other | 12 | 16% |
Unknown | 10 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 17 | 22% |
Biochemistry, Genetics and Molecular Biology | 13 | 17% |
Psychology | 13 | 17% |
Agricultural and Biological Sciences | 8 | 10% |
Neuroscience | 6 | 8% |
Other | 5 | 6% |
Unknown | 15 | 19% |