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The compensatory enrichment of sphingosine -1- phosphate harbored on glycated high-density lipoprotein restores endothelial protective function in type 2 diabetes mellitus

Overview of attention for article published in Cardiovascular Diabetology, April 2014
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1 X user
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1 Google+ user

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27 Mendeley
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Title
The compensatory enrichment of sphingosine -1- phosphate harbored on glycated high-density lipoprotein restores endothelial protective function in type 2 diabetes mellitus
Published in
Cardiovascular Diabetology, April 2014
DOI 10.1186/1475-2840-13-82
Pubmed ID
Authors

Xunliang Tong, Pu Lv, Anna V Mathew, Donghui Liu, Chenguang Niu, Yan Wang, Liang Ji, Jizhao Li, Zhiwei Fu, Bing Pan, Subramaniam Pennathur, Lemin Zheng, Yining Huang

Abstract

Glycation of high-density lipoprotein (HDL) decreases its ability to induce cyclooxygenase-2 (COX-2) expression and prostacyclin I-2 (PGI-2) release in endothelial cells. Whether lipid content of HDL, especially sphingosine-1-phosphate (S1P), plays any specific role in restoring the protective function of HDL in type 2 diabetes mellitus (T2DM) is still unknown.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 27 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 33%
Student > Doctoral Student 3 11%
Professor > Associate Professor 3 11%
Student > Bachelor 2 7%
Student > Master 2 7%
Other 3 11%
Unknown 5 19%
Readers by discipline Count As %
Medicine and Dentistry 8 30%
Biochemistry, Genetics and Molecular Biology 3 11%
Agricultural and Biological Sciences 2 7%
Engineering 2 7%
Pharmacology, Toxicology and Pharmaceutical Science 1 4%
Other 4 15%
Unknown 7 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 April 2014.
All research outputs
#14,195,272
of 22,754,104 outputs
Outputs from Cardiovascular Diabetology
#709
of 1,369 outputs
Outputs of similar age
#120,316
of 226,772 outputs
Outputs of similar age from Cardiovascular Diabetology
#8
of 16 outputs
Altmetric has tracked 22,754,104 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,369 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.8. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,772 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.