Title |
Inability of myalgic encephalomyelitis/chronic fatigue syndrome patients to reproduce VO2peak indicates functional impairment
|
---|---|
Published in |
Journal of Translational Medicine, April 2014
|
DOI | 10.1186/1479-5876-12-104 |
Pubmed ID | |
Authors |
Betsy A Keller, John Luke Pryor, Ludovic Giloteaux |
Abstract |
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a multi-system illness characterized, in part, by increased fatigue following minimal exertion, cognitive impairment, poor recovery to physical and other stressors, in addition to other symptoms. Unlike healthy subjects and other diseased populations who reproduce objective physiological measures during repeat cardiopulmonary exercise tests (CPETs), ME/CFS patients have been reported to fail to reproduce results in a second CPET performed one day after an initial CPET. If confirmed, a disparity between a first and second CPET could serve to identify individuals with ME/CFS, would be able to document their extent of disability, and could also provide a physiological basis for prescribing physical activity as well as a metric of functional impairment. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 63 | 16% |
United States | 56 | 14% |
Australia | 12 | 3% |
Spain | 12 | 3% |
Canada | 12 | 3% |
Netherlands | 10 | 3% |
Germany | 9 | 2% |
Norway | 3 | <1% |
France | 3 | <1% |
Other | 20 | 5% |
Unknown | 192 | 49% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 347 | 89% |
Practitioners (doctors, other healthcare professionals) | 19 | 5% |
Scientists | 17 | 4% |
Science communicators (journalists, bloggers, editors) | 8 | 2% |
Unknown | 1 | <1% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | <1% |
Norway | 1 | <1% |
Unknown | 135 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 25 | 18% |
Student > Ph. D. Student | 16 | 12% |
Student > Master | 13 | 9% |
Student > Bachelor | 9 | 7% |
Other | 8 | 6% |
Other | 24 | 18% |
Unknown | 42 | 31% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 24 | 18% |
Sports and Recreations | 12 | 9% |
Agricultural and Biological Sciences | 9 | 7% |
Nursing and Health Professions | 8 | 6% |
Psychology | 8 | 6% |
Other | 30 | 22% |
Unknown | 46 | 34% |