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A high-content imaging assay for the quantification of the Burkholderia pseudomallei induced multinucleated giant cell (MNGC) phenotype in murine macrophages

Overview of attention for article published in BMC Microbiology, April 2014
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Mentioned by

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1 tweeter

Citations

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14 Dimensions

Readers on

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45 Mendeley
Summary Twitter Dimensions citations
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Title
A high-content imaging assay for the quantification of the Burkholderia pseudomallei induced multinucleated giant cell (MNGC) phenotype in murine macrophages
Published in
BMC Microbiology, April 2014
DOI 10.1186/1471-2180-14-98
Pubmed ID
24750902
Authors

Gianluca Pegoraro, Brett P Eaton, Ricky L Ulrich, Douglas J Lane, Jenifer F Ojeda, Sina Bavari, David DeShazer, Rekha G Panchal

Abstract

Burkholderia pseudomallei (Bp), a Gram-negative, motile, facultative intracellular bacterium is the causative agent of melioidosis in humans and animals. The Bp genome encodes a repertoire of virulence factors, including the cluster 3 type III secretion system (T3SS-3), the cluster 1 type VI secretion system (T6SS-1), and the intracellular motility protein BimA, that enable the pathogen to invade both phagocytic and non-phagocytic cells. A unique hallmark of Bp infection both in vitro and in vivo is its ability to induce cell-to-cell fusion of macrophages to form multinucleated giant cells (MNGCs), which to date are semi-quantitatively reported following visual inspection.

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Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 45 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 24%
Student > Master 7 16%
Student > Bachelor 6 13%
Other 5 11%
Student > Doctoral Student 4 9%
Other 5 11%
Unknown 7 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 13 29%
Biochemistry, Genetics and Molecular Biology 8 18%
Immunology and Microbiology 7 16%
Nursing and Health Professions 2 4%
Unspecified 1 2%
Other 6 13%
Unknown 8 18%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 April 2014.
All research outputs
#15,299,919
of 22,754,104 outputs
Outputs from BMC Microbiology
#1,761
of 3,181 outputs
Outputs of similar age
#133,871
of 226,936 outputs
Outputs of similar age from BMC Microbiology
#24
of 44 outputs
Altmetric has tracked 22,754,104 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,181 research outputs from this source. They receive a mean Attention Score of 4.1. This one is in the 37th percentile – i.e., 37% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,936 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 44 others from the same source and published within six weeks on either side of this one. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.

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