↓ Skip to main content

Historical contingency and the gradual evolution of metabolic properties in central carbon and genome-scale metabolisms

Overview of attention for article published in BMC Systems Biology, April 2014
Altmetric Badge

About this Attention Score

  • Good Attention Score compared to outputs of the same age (70th percentile)
  • Good Attention Score compared to outputs of the same age and source (77th percentile)

Mentioned by

twitter
5 X users

Citations

dimensions_citation
10 Dimensions

Readers on

mendeley
56 Mendeley
citeulike
2 CiteULike
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Historical contingency and the gradual evolution of metabolic properties in central carbon and genome-scale metabolisms
Published in
BMC Systems Biology, April 2014
DOI 10.1186/1752-0509-8-48
Pubmed ID
Authors

Aditya Barve, Sayed-Rzgar Hosseini, Olivier C Martin, Andreas Wagner

Abstract

A metabolism can evolve through changes in its biochemical reactions that are caused by processes such as horizontal gene transfer and gene deletion. While such changes need to preserve an organism's viability in its environment, they can modify other important properties, such as a metabolism's maximal biomass synthesis rate and its robustness to genetic and environmental change. Whether such properties can be modulated in evolution depends on whether all or most viable metabolisms - those that can synthesize all essential biomass precursors - are connected in a space of all possible metabolisms. Connectedness means that any two viable metabolisms can be converted into one another through a sequence of single reaction changes that leave viability intact. If the set of viable metabolisms is disconnected and highly fragmented, then historical contingency becomes important and restricts the alteration of metabolic properties, as well as the number of novel metabolic phenotypes accessible in evolution.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 1 2%
Germany 1 2%
Netherlands 1 2%
France 1 2%
Brazil 1 2%
Canada 1 2%
Singapore 1 2%
United States 1 2%
Unknown 48 86%

Demographic breakdown

Readers by professional status Count As %
Researcher 14 25%
Student > Ph. D. Student 11 20%
Student > Master 6 11%
Professor 5 9%
Student > Doctoral Student 4 7%
Other 11 20%
Unknown 5 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 25 45%
Biochemistry, Genetics and Molecular Biology 10 18%
Social Sciences 2 4%
Computer Science 2 4%
Chemistry 2 4%
Other 6 11%
Unknown 9 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 November 2014.
All research outputs
#7,169,303
of 23,577,654 outputs
Outputs from BMC Systems Biology
#266
of 1,139 outputs
Outputs of similar age
#67,578
of 228,568 outputs
Outputs of similar age from BMC Systems Biology
#6
of 27 outputs
Altmetric has tracked 23,577,654 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 1,139 research outputs from this source. They receive a mean Attention Score of 3.6. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 228,568 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.