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Fear extinction requires Arc/Arg3.1 expression in the basolateral amygdala

Overview of attention for article published in Molecular Brain, April 2014
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Title
Fear extinction requires Arc/Arg3.1 expression in the basolateral amygdala
Published in
Molecular Brain, April 2014
DOI 10.1186/1756-6606-7-30
Pubmed ID
Authors

Kousuke Onoue, Daisuke Nakayama, Yuji Ikegaya, Norio Matsuki, Hiroshi Nomura

Abstract

Prolonged re-exposure to a fear-eliciting cue in the absence of an aversive event extinguishes the fear response to the cue, and has been clinically used as an exposure therapy. Arc (also known as Arg3.1) is implicated in synaptic and experience-dependent plasticity. Arc is regulated by the transcription factor cAMP response element binding protein, which is upregulated with and necessary for fear extinction. Because Arc expression is also activated with fear extinction, we hypothesized that Arc expression is required for fear extinction.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 62 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Unknown 61 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 13 21%
Student > Ph. D. Student 12 19%
Student > Master 8 13%
Student > Bachelor 6 10%
Professor 4 6%
Other 12 19%
Unknown 7 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 20 32%
Neuroscience 20 32%
Biochemistry, Genetics and Molecular Biology 7 11%
Psychology 3 5%
Medicine and Dentistry 2 3%
Other 3 5%
Unknown 7 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 April 2014.
All research outputs
#18,371,293
of 22,754,104 outputs
Outputs from Molecular Brain
#858
of 1,106 outputs
Outputs of similar age
#164,078
of 227,083 outputs
Outputs of similar age from Molecular Brain
#16
of 21 outputs
Altmetric has tracked 22,754,104 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,106 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 227,083 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 21 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.