Title |
Ventriculoarterial decoupling in human septic shock
|
---|---|
Published in |
Critical Care, April 2014
|
DOI | 10.1186/cc13842 |
Pubmed ID | |
Authors |
Fabio Guarracino, Baldassare Ferro, Andrea Morelli, Pietro Bertini, Rubia Baldassarri, Michael R Pinsky |
Abstract |
Septic shock is the most severe manifestation of sepsis. It is characterized as a hypotensive cardiovascular state associated with multiorgan dysfunction and metabolic disturbances. Management of septic shock is targeted at preserving adequate organ perfusion pressure without precipitating pulmonary edema or massive volume overload. Cardiac dysfunction often occurs in septic shock patients and can significantly affect outcomes. One physiologic approach to detect the interaction between the heart and the circulation when both are affected is to examine ventriculoarterial coupling, which is defined by the ratio of arterial elastance (Ea) to left ventricular end-systolic elastance (Ees). In this study, we analyzed ventriculoarterial coupling in a cohort of patients admitted to ICUs who presented with vs without septic shock. |
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Mendeley readers
Geographical breakdown
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