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Abnormal expression of A20 and its regulated genes in peripheral blood from patients with lymphomas

Overview of attention for article published in Cancer Cell International, April 2014
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Title
Abnormal expression of A20 and its regulated genes in peripheral blood from patients with lymphomas
Published in
Cancer Cell International, April 2014
DOI 10.1186/1475-2867-14-36
Pubmed ID
Authors

Xu Wang, Yan Xu, Lichan Liang, Yi Xu, Chunyan Wang, Liang Wang, Shaohua Chen, Lijian Yang, Xiuli Wu, Bo Li, Gengxin Luo, Huo Tan, Wenyu Li, Yangqiu Li

Abstract

Cell-mediated immunity is often suppressed in patients with hematological malignancies. Recently, we found that low T cell receptor (TCR)-CD3 signaling was related to abnormal expression of the negative regulator of nuclear factor kappa B (NF-κB) A20 in acute myeloid leukemia. To investigate the characteristics of T cell immunodeficiency in lymphomas, we analyzed the expression features of A20 and its upstream regulating factor mucosa-associated lymphoid tissue lymphoma translocation gene 1 (MALT1) and genes downstream of NF-κB in patients with different lymphoma subtypes, including T cell non-Hodgkin lymphoma (T-NHL), B cell non-Hodgkin lymphoma (B-NHL) and NK/T cell lymphoma (NK/T-CL).

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 8%
Unknown 11 92%

Demographic breakdown

Readers by professional status Count As %
Other 3 25%
Student > Ph. D. Student 3 25%
Student > Bachelor 1 8%
Researcher 1 8%
Student > Postgraduate 1 8%
Other 0 0%
Unknown 3 25%
Readers by discipline Count As %
Agricultural and Biological Sciences 2 17%
Medicine and Dentistry 2 17%
Nursing and Health Professions 2 17%
Biochemistry, Genetics and Molecular Biology 1 8%
Immunology and Microbiology 1 8%
Other 1 8%
Unknown 3 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 May 2014.
All research outputs
#13,408,116
of 22,754,104 outputs
Outputs from Cancer Cell International
#645
of 1,792 outputs
Outputs of similar age
#111,616
of 226,896 outputs
Outputs of similar age from Cancer Cell International
#5
of 10 outputs
Altmetric has tracked 22,754,104 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,792 research outputs from this source. They receive a mean Attention Score of 3.8. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,896 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.