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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Clusterin silencing inhibits proliferation and reduces invasion in human laryngeal squamous carcinoma cells
|
|---|---|
| Published in |
World Journal of Surgical Oncology, April 2014
|
| DOI | 10.1186/1477-7819-12-124 |
| Pubmed ID | |
| Authors |
Qianjin Wang, Weiyan Cao, Quancai Su, Zimin Liu, Lin Zhang |
| Abstract |
Clusterin is, in its major form, a secreted heterodimeric disulfide-linked glycoprotein (sCLU), which plays important roles in cell survival and death. In laryngeal squamous cell carcinomas (LSCC), sCLU is up-regulated and its expression is related to the invasiveness of these tumors. The purpose of this study was to explore the inhibiting role of sCLU gene silence in the invasive ability and growth of Hep-2 human laryngeal squamous carcinoma cells (Hep-2) by transfection of short hairpin RNA expression plasmids against sCLU (sCLU-shRNA) (in vivo) or small interference RNA (sCLU-siRNA) (in vitro). |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 21 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 5 | 24% |
| Student > Ph. D. Student | 3 | 14% |
| Other | 2 | 10% |
| Researcher | 2 | 10% |
| Student > Master | 2 | 10% |
| Other | 4 | 19% |
| Unknown | 3 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 7 | 33% |
| Medicine and Dentistry | 4 | 19% |
| Biochemistry, Genetics and Molecular Biology | 3 | 14% |
| Immunology and Microbiology | 1 | 5% |
| Unknown | 6 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 April 2014.
All research outputs
#18,371,293
of 22,754,104 outputs
Outputs from World Journal of Surgical Oncology
#1,013
of 2,042 outputs
Outputs of similar age
#163,943
of 226,896 outputs
Outputs of similar age from World Journal of Surgical Oncology
#25
of 52 outputs
Altmetric has tracked 22,754,104 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,042 research outputs from this source. They receive a mean Attention Score of 2.0. This one is in the 22nd percentile – i.e., 22% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,896 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 52 others from the same source and published within six weeks on either side of this one. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.