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X Demographics
Mendeley readers
Attention Score in Context
| Title |
A 3′UTR polymorphism modulates mRNA stability of the oncogene and drug target Polo-like Kinase 1
|
|---|---|
| Published in |
Molecular Cancer, April 2014
|
| DOI | 10.1186/1476-4598-13-87 |
| Pubmed ID | |
| Authors |
Neval Akdeli, Kathrin Riemann, Jana Westphal, Jochen Hess, Winfried Siffert, Hagen S Bachmann |
| Abstract |
The Polo-like Kinase 1 (PLK1) protein regulates cell cycle progression and is overexpressed in many malignant tissues. Overexpression is associated with poor prognosis in several cancer entities, whereby expression of PLK1 shows high inter-individual variability. Although PLK1 is extensively studied, not much is known about the genetic variability of the PLK1 gene. The function of PLK1 and the expression of the corresponding gene could be influenced by genomic variations. Hence, we investigated the gene for functional polymorphisms. Such polymorphisms could be useful to investigate whether PLK1 alters the risk for and the course of cancer and they could have an impact on the response to PLK1 inhibitors. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 21 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 6 | 29% |
| Student > Ph. D. Student | 3 | 14% |
| Student > Master | 3 | 14% |
| Student > Bachelor | 2 | 10% |
| Lecturer | 1 | 5% |
| Other | 4 | 19% |
| Unknown | 2 | 10% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 9 | 43% |
| Agricultural and Biological Sciences | 3 | 14% |
| Medicine and Dentistry | 2 | 10% |
| Nursing and Health Professions | 2 | 10% |
| Unspecified | 1 | 5% |
| Other | 2 | 10% |
| Unknown | 2 | 10% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 April 2014.
All research outputs
#18,371,293
of 22,754,104 outputs
Outputs from Molecular Cancer
#1,288
of 1,717 outputs
Outputs of similar age
#163,943
of 226,896 outputs
Outputs of similar age from Molecular Cancer
#45
of 53 outputs
Altmetric has tracked 22,754,104 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,717 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 14th percentile – i.e., 14% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,896 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 53 others from the same source and published within six weeks on either side of this one. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.