Title |
A comprehensive analysis of Helicobacter pylori plasticity zones reveals that they are integrating conjugative elements with intermediate integration specificity
|
---|---|
Published in |
BMC Genomics, April 2014
|
DOI | 10.1186/1471-2164-15-310 |
Pubmed ID | |
Authors |
Wolfgang Fischer, Ute Breithaupt, Beate Kern, Stella I Smith, Carolin Spicher, Rainer Haas |
Abstract |
The human gastric pathogen Helicobacter pylori is a paradigm for chronic bacterial infections. Its persistence in the stomach mucosa is facilitated by several mechanisms of immune evasion and immune modulation, but also by an unusual genetic variability which might account for the capability to adapt to changing environmental conditions during long-term colonization. This variability is reflected by the fact that almost each infected individual is colonized by a genetically unique strain. Strain-specific genes are dispersed throughout the genome, but clusters of genes organized as genomic islands may also collectively be present or absent. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 50% |
Norway | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 1 | 50% |
Members of the public | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Brazil | 1 | 1% |
Unknown | 70 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 21 | 30% |
Researcher | 10 | 14% |
Student > Master | 10 | 14% |
Student > Doctoral Student | 5 | 7% |
Student > Postgraduate | 5 | 7% |
Other | 11 | 15% |
Unknown | 9 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 20 | 28% |
Biochemistry, Genetics and Molecular Biology | 18 | 25% |
Immunology and Microbiology | 5 | 7% |
Medicine and Dentistry | 4 | 6% |
Linguistics | 2 | 3% |
Other | 5 | 7% |
Unknown | 17 | 24% |