Title |
The prophylactic use of C1 inhibitor in hereditary angioedema patients undergoing invasive surgical procedures: a retrospective study
|
---|---|
Published in |
Allergy, Asthma & Clinical Immunology, April 2014
|
DOI | 10.1186/1710-1492-10-17 |
Pubmed ID | |
Authors |
Geneviève Gavigan, William H Yang, Stephanie Santucci, Rachel Harrison, Jacob Karsh |
Abstract |
Hereditary Angioedema (HAE) is a rare autosomal dominant condition characterized by episodic angioedema, which may be triggered by invasive procedures and surgery. C1 inhibitor (C1 INH) was approved in the United States and Canada in 2009 and 2010, respectively, for the treatment of acute attacks. Most recently in April 2013, it was approved in Europe for short-term prophylaxis (STP), prior to medical, dental, or surgical procedures, to prevent HAE attacks in both children and adults. Currently, C1 INH is not approved in Canada or the United States for STP of HAE attacks. Our objective was to demonstrate the effectiveness of C1 INH as a short-term prophylactic treatment for patients with Type I HAE undergoing invasive surgical procedures. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 6% |
Turkey | 1 | 6% |
Unknown | 16 | 89% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 4 | 22% |
Student > Bachelor | 2 | 11% |
Student > Ph. D. Student | 2 | 11% |
Student > Master | 2 | 11% |
Student > Doctoral Student | 1 | 6% |
Other | 4 | 22% |
Unknown | 3 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 12 | 67% |
Agricultural and Biological Sciences | 1 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 6% |
Unknown | 4 | 22% |