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Mesenchymal stem cells of dental origin as promising tools for neuroregeneration

Overview of attention for article published in Stem Cell Research & Therapy, April 2014
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Title
Mesenchymal stem cells of dental origin as promising tools for neuroregeneration
Published in
Stem Cell Research & Therapy, April 2014
DOI 10.1186/scrt450
Pubmed ID
Authors

Gábor Varga, Gábor Gerber

Abstract

The adult central nervous system has only a very limited ability to newly generate lost neurons and glial cells. Therefore, its self-renewal efficiency after degenerative damage or acute injuries is very limited. Mesenchymal stem cells of various tissue origins, including dental tissues, are among the most promising tools in stem cell therapeutic approaches. In a previous issue of Stem Cell Research & Therapy, Ellis and colleagues demonstrated the neuronal differentiation potential of murine dental pulp stem cells. Our commentary discusses the significance of the study, the parallel efforts of other laboratories, the present limitations of neuronal transdifferentiation using cells obtained by various available methods, and the possible breakthrough by combining the various cellular resources with pharmacological and tissue engineering methods.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Colombia 1 2%
Brazil 1 2%
Unknown 46 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 15%
Student > Doctoral Student 6 13%
Researcher 6 13%
Student > Bachelor 4 8%
Student > Master 4 8%
Other 6 13%
Unknown 15 31%
Readers by discipline Count As %
Medicine and Dentistry 10 21%
Biochemistry, Genetics and Molecular Biology 6 13%
Agricultural and Biological Sciences 4 8%
Nursing and Health Professions 3 6%
Business, Management and Accounting 1 2%
Other 8 17%
Unknown 16 33%