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QGRS-Conserve: a computational method for discovering evolutionarily conserved G-quadruplex motifs

Overview of attention for article published in Human Genomics, May 2014
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Title
QGRS-Conserve: a computational method for discovering evolutionarily conserved G-quadruplex motifs
Published in
Human Genomics, May 2014
DOI 10.1186/1479-7364-8-8
Pubmed ID
Authors

Scott Frees, Camille Menendez, Matt Crum, Paramjeet S Bagga

Abstract

Nucleic acids containing guanine tracts can form quadruplex structures via non-Watson-Crick base pairing. Formation of G-quadruplexes is associated with the regulation of important biological functions such as transcription, genetic instability, DNA repair, DNA replication, epigenetic mechanisms, regulation of translation, and alternative splicing. G-quadruplexes play important roles in human diseases and are being considered as targets for a variety of therapies. Identification of functional G-quadruplexes and the study of their overall distribution in genomes and transcriptomes is an important pursuit. Traditional computational methods map sequence motifs capable of forming G-quadruplexes but have difficulty in distinguishing motifs that occur by chance from ones which fold into G-quadruplexes.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 87 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 1 1%
Unknown 86 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 17%
Student > Master 12 14%
Researcher 7 8%
Student > Bachelor 6 7%
Student > Doctoral Student 4 5%
Other 14 16%
Unknown 29 33%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 23 26%
Agricultural and Biological Sciences 13 15%
Chemistry 8 9%
Medicine and Dentistry 5 6%
Computer Science 3 3%
Other 3 3%
Unknown 32 37%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 June 2014.
All research outputs
#19,962,154
of 25,394,764 outputs
Outputs from Human Genomics
#439
of 564 outputs
Outputs of similar age
#169,443
of 242,247 outputs
Outputs of similar age from Human Genomics
#3
of 3 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 564 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.0. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 242,247 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.