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Epidermal growth factor-receptor activation modulates Src-dependent resistance to lapatinib in breast cancer models

Overview of attention for article published in Breast Cancer Research, May 2014
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  • Average Attention Score compared to outputs of the same age
  • Above-average Attention Score compared to outputs of the same age and source (51st percentile)

Mentioned by

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2 X users

Citations

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58 Dimensions

Readers on

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83 Mendeley
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Title
Epidermal growth factor-receptor activation modulates Src-dependent resistance to lapatinib in breast cancer models
Published in
Breast Cancer Research, May 2014
DOI 10.1186/bcr3650
Pubmed ID
Authors

Luigi Formisano, Lucia Nappi, Roberta Rosa, Roberta Marciano, Claudia D’Amato, Valentina D’Amato, Vincenzo Damiano, Lucia Raimondo, Francesca Iommelli, Antonella Scorziello, Giancarlo Troncone, Bianca Maria Veneziani, Sarah J Parsons, Sabino De Placido, Roberto Bianco

Abstract

Src tyrosine kinase overactivation has been correlated with a poor response to human epidermal growth factor receptor 2 (HER2) inhibitors in breast cancer. To identify the mechanism by which Src overexpression sustains this resistance, we tested a panel of breast cancer cell lines either sensitive or resistant to lapatinib.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 83 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 1%
Unknown 82 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 22 27%
Student > Bachelor 14 17%
Student > Master 9 11%
Researcher 8 10%
Professor > Associate Professor 4 5%
Other 12 14%
Unknown 14 17%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 25 30%
Agricultural and Biological Sciences 15 18%
Medicine and Dentistry 13 16%
Pharmacology, Toxicology and Pharmaceutical Science 8 10%
Unspecified 1 1%
Other 5 6%
Unknown 16 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 June 2014.
All research outputs
#16,045,990
of 25,371,288 outputs
Outputs from Breast Cancer Research
#1,429
of 2,052 outputs
Outputs of similar age
#132,000
of 241,897 outputs
Outputs of similar age from Breast Cancer Research
#16
of 37 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,052 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.2. This one is in the 28th percentile – i.e., 28% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 241,897 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 37 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.