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PAR2-Mediated Upregulation of BDNF Contributes to Central Sensitization in Bone Cancer Pain

Overview of attention for article published in Molecular Pain, January 2014
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Title
PAR2-Mediated Upregulation of BDNF Contributes to Central Sensitization in Bone Cancer Pain
Published in
Molecular Pain, January 2014
DOI 10.1186/1744-8069-10-28
Pubmed ID
Authors

Yanju Bao, Wei Hou, Rui Liu, Yebo Gao, Xiangying Kong, Liping Yang, Zhan Shi, Weidong Li, Honggang Zheng, Shulong Jiang, Conghuang Li, Yinggang Qin, Baojin Hua

Abstract

Bone cancer pain is currently a major clinical challenge for the management of cancer patients, and the cellular and molecular mechanisms underlying the spinal sensitization remain unclear. While several studies demonstrated the critical role of proteinase-activated receptor (PAR2) in the pathogenesis of several types of inflammatory or neuropathic pain, the involvement of spinal PAR2 and the pertinent signaling in the central sensitization is not determined yet in the rodent model of bone cancer pain.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Malaysia 1 2%
Canada 1 2%
Unknown 43 96%

Demographic breakdown

Readers by professional status Count As %
Student > Master 10 22%
Student > Ph. D. Student 8 18%
Professor > Associate Professor 4 9%
Professor 3 7%
Other 3 7%
Other 7 16%
Unknown 10 22%
Readers by discipline Count As %
Medicine and Dentistry 8 18%
Agricultural and Biological Sciences 7 16%
Neuroscience 7 16%
Biochemistry, Genetics and Molecular Biology 4 9%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Other 5 11%
Unknown 12 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 May 2014.
All research outputs
#22,778,604
of 25,394,764 outputs
Outputs from Molecular Pain
#595
of 670 outputs
Outputs of similar age
#280,610
of 319,416 outputs
Outputs of similar age from Molecular Pain
#51
of 58 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 670 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 319,416 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 58 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.