Title |
Erythrocyte selenium concentration predicts intensive care unit and hospital mortality in patients with septic shock: a prospective observational study
|
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Published in |
Critical Care, May 2014
|
DOI | 10.1186/cc13860 |
Pubmed ID | |
Authors |
Nara Aline Costa, Ana Lúcia Gut, José Alexandre Coelho Pimentel, Silvia Maria Franciscato Cozzolino, Paula Schmidt Azevedo, Ana Angélica Henrique Fernandes, Bertha Furlan Polegato, Suzana Erico Tanni, Rafael Dezen Gaiolla, Leonardo Antonio Mamede Zornoff, Sergio Alberto Rupp de Paiva, Marcos Ferreira Minicucci |
Abstract |
Selenoenzymes can modulate the extent of oxidative stress, which is recognized as a key feature of septic shock. The pathophysiologic role of erythrocyte selenium concentration in patients with septic shock remains unknown. Therefore, the objective of this study was to evaluate the association of erythrocyte selenium concentration with glutathione peroxidase (GPx1) activity, GPx1 polymorphisms and with ICU and hospital mortality in septic shock patients. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Canada | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Members of the public | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Colombia | 1 | 2% |
Romania | 1 | 2% |
Unknown | 52 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 8 | 15% |
Student > Master | 8 | 15% |
Student > Postgraduate | 6 | 11% |
Student > Bachelor | 5 | 9% |
Student > Doctoral Student | 3 | 6% |
Other | 12 | 22% |
Unknown | 12 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 25 | 46% |
Nursing and Health Professions | 5 | 9% |
Business, Management and Accounting | 2 | 4% |
Veterinary Science and Veterinary Medicine | 1 | 2% |
Agricultural and Biological Sciences | 1 | 2% |
Other | 5 | 9% |
Unknown | 15 | 28% |