Title |
A case of EDTA-dependent pseudothrombocytopenia: simple recognition of an underdiagnosed and misleading phenomenon
|
---|---|
Published in |
BMC Clinical Pathology, May 2014
|
DOI | 10.1186/1472-6890-14-19 |
Pubmed ID | |
Authors |
Michael Nagler, Peter Keller, Daniel Siegrist, Lorenzo Alberio |
Abstract |
EDTA-dependent pseudothrombocytopenia (EDTA-PTCP) is a common laboratory phenomenon with a prevalence ranging from 0.1-2% in hospitalized patients to 15-17% in outpatients evaluated for isolated thrombocytopenia. Despite its harmlessness, EDTA-PTCP frequently leads to time-consuming, costly and even invasive diagnostic investigations. EDTA-PTCP is often overlooked because blood smears are not evaluated visually in routine practice and histograms as well as warning flags of hematology analyzers are not interpreted correctly. Nonetheless, EDTA-PTCP may be diagnosed easily even by general practitioners without any experiences in blood film examinations. This is the first report illustrating the typical patterns of a platelet (PLT) and white blood cell (WBC) histograms of hematology analyzers. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 4 | 80% |
Unknown | 1 | 20% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 5 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 2% |
Unknown | 48 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 11 | 22% |
Student > Bachelor | 7 | 14% |
Student > Postgraduate | 4 | 8% |
Other | 3 | 6% |
Researcher | 3 | 6% |
Other | 5 | 10% |
Unknown | 16 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 18 | 37% |
Biochemistry, Genetics and Molecular Biology | 5 | 10% |
Immunology and Microbiology | 4 | 8% |
Agricultural and Biological Sciences | 3 | 6% |
Computer Science | 1 | 2% |
Other | 3 | 6% |
Unknown | 15 | 31% |