Title |
Haemophilus influenzae porine omp P2 gene transfer mediated by graphene oxide nanoparticles with effects on transformation process and virulence bacterial capacity
|
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Published in |
Journal of Nanobiotechnology, April 2014
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DOI | 10.1186/1477-3155-12-14 |
Pubmed ID | |
Authors |
Julia Nogueira Varela, Cecília Cecília Krähenbühl Amstalden, Rafaella Fabiana Carneiro Pereira, Luciana Maria de Hollanda, Helder José Ceragioli, Vitor Baranauskas, Marcelo Lancellotti |
Abstract |
H. influenzae is a natural competent bacterium that can uptake DNA from the environment and recombine into bacterial genome. The outbreaks of Brazilian purpuric fever, heavily polluted areas of a different H. influenzae biogroup - aegyptius - as well as gene transference between Neisseria meningitis make the transformation process an important evolutionary factor. This work studied the horizontal transference of the ompP2 gene from a multiresistant strain of H. influenzae 07 (NTHi), under the influence of graphene oxide nanoparticles in order to mimic an atmosphere rich in suspended particles and this way verify if the CFU transformants number was increased. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Brazil | 1 | 5% |
Unknown | 20 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 4 | 19% |
Researcher | 4 | 19% |
Student > Doctoral Student | 2 | 10% |
Student > Bachelor | 2 | 10% |
Other | 2 | 10% |
Other | 6 | 29% |
Unknown | 1 | 5% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 3 | 14% |
Biochemistry, Genetics and Molecular Biology | 3 | 14% |
Immunology and Microbiology | 3 | 14% |
Medicine and Dentistry | 3 | 14% |
Social Sciences | 2 | 10% |
Other | 3 | 14% |
Unknown | 4 | 19% |