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Heat shock protein 60: an endogenous inducer of dopaminergic cell death in Parkinson disease

Overview of attention for article published in Journal of Neuroinflammation, May 2014
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Title
Heat shock protein 60: an endogenous inducer of dopaminergic cell death in Parkinson disease
Published in
Journal of Neuroinflammation, May 2014
DOI 10.1186/1742-2094-11-86
Pubmed ID
Authors

Carmen Noelker, Lydie Morel, Anke Osterloh, Daniel Alvarez-Fischer, Thomas Lescot, Minka Breloer, Maike Gold, Wolfgang H Oertel, Carmen Henze, Patrick P Michel, Richard C Dodel, Lixia Lu, Etienne C Hirsch, Stéphane Hunot, Andreas Hartmann

Abstract

Increasing evidence suggests that inflammation associated with microglial cell activation in the substantia nigra (SN) of patients with Parkinson disease (PD) is not only a consequence of neuronal degeneration, but may actively sustain dopaminergic (DA) cell loss over time. We aimed to study whether the intracellular chaperone heat shock protein 60 (Hsp60) could serve as a signal of CNS injury for activation of microglial cells.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Denmark 1 2%
France 1 2%
Unknown 51 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 21%
Student > Master 9 17%
Researcher 8 15%
Student > Bachelor 5 9%
Student > Doctoral Student 4 8%
Other 4 8%
Unknown 12 23%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 23%
Medicine and Dentistry 8 15%
Neuroscience 8 15%
Biochemistry, Genetics and Molecular Biology 6 11%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Other 1 2%
Unknown 16 30%