Title |
Replication by the Epistasis Project of the interaction between the genes for IL-6 and IL-10 in the risk of Alzheimer's disease
|
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Published in |
Journal of Neuroinflammation, August 2009
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DOI | 10.1186/1742-2094-6-22 |
Pubmed ID | |
Authors |
Onofre Combarros, Cornelia M van Duijn, Naomi Hammond, Olivia Belbin, Alejandro Arias-Vásquez, Mario Cortina-Borja, Michael G Lehmann, Yurii S Aulchenko, Maaike Schuur, Heike Kölsch, Reinhard Heun, Gordon K Wilcock, Kristelle Brown, Patrick G Kehoe, Rachel Harrison, Eliecer Coto, Victoria Alvarez, Panos Deloukas, Ignacio Mateo, Rhian Gwilliam, Kevin Morgan, Donald R Warden, A David Smith, Donald J Lehmann |
Abstract |
Chronic inflammation is a characteristic of Alzheimer's disease (AD). An interaction associated with the risk of AD has been reported between polymorphisms in the regulatory regions of the genes for the pro-inflammatory cytokine, interleukin-6 (IL-6, gene: IL6), and the anti-inflammatory cytokine, interleukin-10 (IL-10, gene: IL10). |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 1% |
Spain | 1 | 1% |
Unknown | 77 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 26 | 33% |
Researcher | 16 | 20% |
Student > Master | 12 | 15% |
Other | 5 | 6% |
Student > Bachelor | 3 | 4% |
Other | 11 | 14% |
Unknown | 6 | 8% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 28 | 35% |
Medicine and Dentistry | 12 | 15% |
Psychology | 7 | 9% |
Neuroscience | 7 | 9% |
Biochemistry, Genetics and Molecular Biology | 6 | 8% |
Other | 9 | 11% |
Unknown | 10 | 13% |