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Leukotriene receptor antagonists for chronic urticaria: a systematic review

Overview of attention for article published in Allergy, Asthma & Clinical Immunology, May 2014
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (85th percentile)
  • Good Attention Score compared to outputs of the same age and source (76th percentile)

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1 news outlet
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2 X users

Citations

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50 Dimensions

Readers on

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62 Mendeley
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Title
Leukotriene receptor antagonists for chronic urticaria: a systematic review
Published in
Allergy, Asthma & Clinical Immunology, May 2014
DOI 10.1186/1710-1492-10-24
Pubmed ID
Authors

Nipun Lakshitha de Silva, Hasitha Damayanthi, Anoja Chamarie Rajapakse, Chaturaka Rodrigo, Senaka Rajapakse

Abstract

A significant proportion of patients with chronic urticaria respond inadequately to first line treatment with antihistamines. Leukotreine receptor antagonists (LTRA) are also used for chronic urticaria, although firm recommendations on their use are lacking. We performed a systematic review of randomised trials to determine the role of LTRA in treatment of chronic urticaria. A search of PUBMED, EMBASE, SCOPUS, LILACS, the Cochrane Central Register of Controlled Trials, and the Web of Science for relevant randomized control trials or cross over studies yielded 10 eligible studies. The heterogeneity of trials were high, preventing valid meta-analysis of data. Most trials indicated that LTRA are not superior to placebo or antihistamine therapy, while combination therapy of LTRA and antihistamines appear to be more efficacious compared to antihistamine alone. The side effect profile and tolerability of this group of drugs is acceptable. The use of LTRA as monotherapy cannot be recommended. LTRA are effective add-on therapy to anti-histamines, and their use in patients responding poorly to antihistamines is justifiable. Further well designed randomized controlled trials with clear and standardized outcome measures are needed to determine the role of LTRA in chronic urticaria.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 62 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Korea, Republic of 1 2%
Unknown 61 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 8 13%
Student > Postgraduate 7 11%
Student > Ph. D. Student 6 10%
Researcher 6 10%
Student > Master 6 10%
Other 10 16%
Unknown 19 31%
Readers by discipline Count As %
Medicine and Dentistry 28 45%
Economics, Econometrics and Finance 3 5%
Pharmacology, Toxicology and Pharmaceutical Science 3 5%
Business, Management and Accounting 1 2%
Agricultural and Biological Sciences 1 2%
Other 5 8%
Unknown 21 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 November 2023.
All research outputs
#3,415,510
of 25,374,917 outputs
Outputs from Allergy, Asthma & Clinical Immunology
#240
of 924 outputs
Outputs of similar age
#32,968
of 241,929 outputs
Outputs of similar age from Allergy, Asthma & Clinical Immunology
#3
of 13 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 924 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.8. This one has gotten more attention than average, scoring higher than 72% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 241,929 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 76% of its contemporaries.