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Frailty in end-stage renal disease: comparing patient, caregiver, and clinician perspectives

Overview of attention for article published in BMC Nephrology, May 2017
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Title
Frailty in end-stage renal disease: comparing patient, caregiver, and clinician perspectives
Published in
BMC Nephrology, May 2017
DOI 10.1186/s12882-017-0558-x
Pubmed ID
Authors

David A. Clark, Usman Khan, Bryce A. Kiberd, Colin C. Turner, Alison Dixon, David Landry, Heather C. Moffatt, Paige A. Moorhouse, Karthik K. Tennankore

Abstract

Frailty is associated with poor outcomes for patients on dialysis and is traditionally measured using tools that assess physical impairment. Alternate measurement tools highlight cognitive and functional domains, requiring clinician, patient, and/or caregiver input. In this study, we compared frailty measures for incident dialysis patients that incorporate patient, clinician, and caregiver perspectives with an aim to contrast the measured prevalence of frailty using tools derived from different conceptual frameworks. A prospective cohort study of incident dialysis patients was conducted between February 2014 and June 2015. Frailty was assessed at dialysis onset using: 1) modified definition of Fried Phenotype (Dialysis Morbidity Mortality Study definition, DMMS); 2) Clinical Frailty Scale (CFS); 3) Frailty Assessment Care Planning Tool (provides CFS grading, FACT-CFS); and 4) Frailty Index (FI). Measures were compared via correlation and sensitivity/specificity analyses. A total of 98 patients participated (mean age of 61 ± 14 years). Participants were primarily Caucasian (91%), male (58%), and the majority started on hemodialysis (83%). The median score for both the CFS and FACT-CFS was 4 (interquartile range of 3-5). The mean FI score was 0.31 (standard deviation ± 0.16). The DMMS identified 78% of patients as frail. The FACT-CFS demonstrated highest correlation (r = 0.71) with the FI, while the DMMS was most sensitive (97%, 100%) and a CFS ≥ 5 most specific (100%, 77%) at corresponding FI cutoff values (>0.21, >0.45). Frailty assessments of incident dialysis patients that include clinician, caregiver and patient perspectives have moderate to strong correlation with the FI. At specified FI cutoff values, the FACT-CFS and DMMS are highly sensitive measures of frailty. The CFS and FACT-CFS may represent viable alternative screening tools in dialysis patients.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 75 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Poland 1 1%
Unknown 74 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 13%
Student > Doctoral Student 10 13%
Student > Master 9 12%
Student > Bachelor 8 11%
Other 6 8%
Other 10 13%
Unknown 22 29%
Readers by discipline Count As %
Medicine and Dentistry 27 36%
Nursing and Health Professions 13 17%
Psychology 4 5%
Agricultural and Biological Sciences 1 1%
Computer Science 1 1%
Other 5 7%
Unknown 24 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 August 2017.
All research outputs
#19,968,026
of 25,402,889 outputs
Outputs from BMC Nephrology
#1,969
of 2,761 outputs
Outputs of similar age
#234,922
of 324,961 outputs
Outputs of similar age from BMC Nephrology
#49
of 66 outputs
Altmetric has tracked 25,402,889 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,761 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one is in the 22nd percentile – i.e., 22% of its peers scored the same or lower than it.
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We're also able to compare this research output to 66 others from the same source and published within six weeks on either side of this one. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.