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Peripheral Nerve Injury and TRPV1-Expressing Primary Afferent C-Fibers Cause Opening of the Blood-Brain Barrier

Overview of attention for article published in Molecular Pain, January 2010
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (77th percentile)
  • Good Attention Score compared to outputs of the same age and source (70th percentile)

Mentioned by

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6 X users
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4 Facebook pages
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1 research highlight platform

Readers on

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157 Mendeley
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Title
Peripheral Nerve Injury and TRPV1-Expressing Primary Afferent C-Fibers Cause Opening of the Blood-Brain Barrier
Published in
Molecular Pain, January 2010
DOI 10.1186/1744-8069-6-74
Pubmed ID
Authors

Simon Beggs, Xue Jun Liu, Chun Kwan, Michael W Salter

Abstract

The blood-brain barrier (BBB) plays the crucial role of limiting exposure of the central nervous system (CNS) to damaging molecules and cells. Dysfunction of the BBB is critical in a broad range of CNS disorders including neurodegeneration, inflammatory or traumatic injury to the CNS, and stroke. In peripheral tissues, the vascular-tissue permeability is normally greater than BBB permeability, but vascular leakage can be induced by efferent discharge activity in primary sensory neurons leading to plasma extravasation into the extravascular space. Whether discharge activity of sensory afferents entering the CNS may open the BBB or blood-spinal cord barrier (BSCB) remains an open question.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 157 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 1%
Chile 1 <1%
Iran, Islamic Republic of 1 <1%
Unknown 153 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 27 17%
Researcher 27 17%
Student > Master 20 13%
Student > Bachelor 16 10%
Other 10 6%
Other 32 20%
Unknown 25 16%
Readers by discipline Count As %
Medicine and Dentistry 35 22%
Neuroscience 33 21%
Agricultural and Biological Sciences 21 13%
Biochemistry, Genetics and Molecular Biology 11 7%
Nursing and Health Professions 8 5%
Other 19 12%
Unknown 30 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 January 2018.
All research outputs
#6,298,484
of 25,374,647 outputs
Outputs from Molecular Pain
#121
of 669 outputs
Outputs of similar age
#38,017
of 172,632 outputs
Outputs of similar age from Molecular Pain
#9
of 30 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 669 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 172,632 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 77% of its contemporaries.
We're also able to compare this research output to 30 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.