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Redundancy of myostatin and growth/differentiation factor 11 function

Overview of attention for article published in BMC Developmental Biology, March 2009
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#38 of 372)
  • High Attention Score compared to outputs of the same age (88th percentile)

Mentioned by

patent
10 patents
facebook
1 Facebook page

Citations

dimensions_citation
146 Dimensions

Readers on

mendeley
156 Mendeley
citeulike
2 CiteULike
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Title
Redundancy of myostatin and growth/differentiation factor 11 function
Published in
BMC Developmental Biology, March 2009
DOI 10.1186/1471-213x-9-24
Pubmed ID
Authors

Alexandra C McPherron, Thanh V Huynh, Se-Jin Lee

Abstract

Myostatin (Mstn) and growth/differentiation factor 11 (Gdf11) are highly related transforming growth factor beta (TGFbeta) family members that play important roles in regulating embryonic development and adult tissue homeostasis. Despite their high degree of sequence identity, targeted mutations in these genes result in non-overlapping phenotypes affecting distinct biological processes. Loss of Mstn in mice causes a doubling of skeletal muscle mass while loss of Gdf11 in mice causes dramatic anterior homeotic transformations of the axial skeleton, kidney agenesis, and an increase in progenitor cell number in several tissues. In order to investigate the possible functional redundancy of myostatin and Gdf11, we analyzed the effect of eliminating the functions of both of these signaling molecules.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 156 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 1%
Germany 1 <1%
Chile 1 <1%
Netherlands 1 <1%
Japan 1 <1%
Canada 1 <1%
Unknown 149 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 34 22%
Student > Ph. D. Student 28 18%
Student > Master 13 8%
Student > Doctoral Student 12 8%
Student > Bachelor 11 7%
Other 33 21%
Unknown 25 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 56 36%
Biochemistry, Genetics and Molecular Biology 34 22%
Medicine and Dentistry 17 11%
Pharmacology, Toxicology and Pharmaceutical Science 7 4%
Sports and Recreations 3 2%
Other 11 7%
Unknown 28 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 November 2023.
All research outputs
#3,314,659
of 23,454,152 outputs
Outputs from BMC Developmental Biology
#38
of 372 outputs
Outputs of similar age
#11,289
of 95,721 outputs
Outputs of similar age from BMC Developmental Biology
#1
of 4 outputs
Altmetric has tracked 23,454,152 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 372 research outputs from this source. They receive a mean Attention Score of 4.4. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 95,721 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them