Title |
Feasibility and safety of high-dose adenosine perfusion cardiovascular magnetic resonance
|
---|---|
Published in |
Critical Reviews in Diagnostic Imaging, November 2010
|
DOI | 10.1186/1532-429x-12-66 |
Pubmed ID | |
Authors |
Theodoros D Karamitsos, Ntobeko AB Ntusi, Jane M Francis, Cameron J Holloway, Saul G Myerson, Stefan Neubauer |
Abstract |
Adenosine is the most widely used vasodilator stress agent for cardiovascular magnetic resonance (CMR) perfusion studies. With the standard dose of 140 mcg/kg/min some patients fail to demonstrate characteristic haemodynamic changes: a significant increase in heart rate (HR) and mild decrease in systolic blood pressure (SBP). Whether an increase in the rate of adenosine infusion would improve peripheral and, likely, coronary vasodilatation in those patients is unknown. The aim of the present study was to assess the tolerance and safety of a high-dose adenosine protocol in patients with inadequate haemodynamic response to the standard adenosine protocol when undergoing CMR perfusion imaging. |
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