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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Extended passaging increases the efficiency of neural differentiation from induced pluripotent stem cells
|
|---|---|
| Published in |
BMC Neuroscience, August 2011
|
| DOI | 10.1186/1471-2202-12-82 |
| Pubmed ID | |
| Authors |
Karl R Koehler, Philippe Tropel, Jonathan W Theile, Takako Kondo, Theodore R Cummins, Stéphane Viville, Eri Hashino |
| Abstract |
The use of induced pluripotent stem cells (iPSCs) for the functional replacement of damaged neurons and in vitro disease modeling is of great clinical relevance. Unfortunately, the capacity of iPSC lines to differentiate into neurons is highly variable, prompting the need for a reliable means of assessing the differentiation capacity of newly derived iPSC cell lines. Extended passaging is emerging as a method of ensuring faithful reprogramming. We adapted an established and efficient embryonic stem cell (ESC) neural induction protocol to test whether iPSCs (1) have the competence to give rise to functional neurons with similar efficiency as ESCs and (2) whether the extent of neural differentiation could be altered or enhanced by increased passaging. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 135 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 2 | 1% |
| Germany | 1 | <1% |
| Australia | 1 | <1% |
| Brazil | 1 | <1% |
| India | 1 | <1% |
| United Kingdom | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 127 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 34 | 25% |
| Researcher | 26 | 19% |
| Student > Bachelor | 18 | 13% |
| Student > Master | 17 | 13% |
| Student > Doctoral Student | 8 | 6% |
| Other | 19 | 14% |
| Unknown | 13 | 10% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 55 | 41% |
| Neuroscience | 20 | 15% |
| Biochemistry, Genetics and Molecular Biology | 18 | 13% |
| Medicine and Dentistry | 12 | 9% |
| Engineering | 6 | 4% |
| Other | 11 | 8% |
| Unknown | 13 | 10% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 November 2013.
All research outputs
#6,373,258
of 22,649,029 outputs
Outputs from BMC Neuroscience
#308
of 1,240 outputs
Outputs of similar age
#35,736
of 120,707 outputs
Outputs of similar age from BMC Neuroscience
#5
of 32 outputs
Altmetric has tracked 22,649,029 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 1,240 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 120,707 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.
We're also able to compare this research output to 32 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.