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Comparison of AMG 416 and cinacalcet in rodent models of uremia

Overview of attention for article published in BMC Nephrology, May 2014
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Title
Comparison of AMG 416 and cinacalcet in rodent models of uremia
Published in
BMC Nephrology, May 2014
DOI 10.1186/1471-2369-15-81
Pubmed ID
Authors

Sarah Walter, Amos Baruch, Shawn T Alexander, Julie Janes, Eiketsu Sho, Jin Dong, Qun Yin, Derek Maclean, Dirk B Mendel, Felix Karim, Randolph M Johnson

Abstract

AMG 416 is a novel peptide agonist of the calcium-sensing receptor (CaSR). This report describes the activity of AMG 416 in two different rodent models of uremia, compared in each case to cinacalcet, an approved therapeutic for secondary hyperparathyroidism (SHPT) in patients with chronic kidney disease on dialysis.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 29 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 29 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 17%
Other 4 14%
Researcher 2 7%
Student > Bachelor 2 7%
Lecturer 1 3%
Other 3 10%
Unknown 12 41%
Readers by discipline Count As %
Medicine and Dentistry 6 21%
Nursing and Health Professions 3 10%
Pharmacology, Toxicology and Pharmaceutical Science 2 7%
Computer Science 1 3%
Biochemistry, Genetics and Molecular Biology 1 3%
Other 2 7%
Unknown 14 48%