Title |
Metabolic network reconstruction and genome-scale model of butanol-producing strain Clostridium beijerinckii NCIMB 8052
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Published in |
BMC Systems Biology, August 2011
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DOI | 10.1186/1752-0509-5-130 |
Pubmed ID | |
Authors |
Caroline B Milne, James A Eddy, Ravali Raju, Soroush Ardekani, Pan-Jun Kim, Ryan S Senger, Yong-Su Jin, Hans P Blaschek, Nathan D Price |
Abstract |
Solventogenic clostridia offer a sustainable alternative to petroleum-based production of butanol--an important chemical feedstock and potential fuel additive or replacement. C. beijerinckii is an attractive microorganism for strain design to improve butanol production because it (i) naturally produces the highest recorded butanol concentrations as a byproduct of fermentation; and (ii) can co-ferment pentose and hexose sugars (the primary products from lignocellulosic hydrolysis). Interrogating C. beijerinckii metabolism from a systems viewpoint using constraint-based modeling allows for simulation of the global effect of genetic modifications. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 7 | 3% |
Iran, Islamic Republic of | 2 | <1% |
Portugal | 1 | <1% |
Netherlands | 1 | <1% |
France | 1 | <1% |
Australia | 1 | <1% |
Colombia | 1 | <1% |
Singapore | 1 | <1% |
Germany | 1 | <1% |
Other | 2 | <1% |
Unknown | 205 | 92% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 61 | 27% |
Researcher | 54 | 24% |
Student > Master | 26 | 12% |
Student > Bachelor | 14 | 6% |
Professor > Associate Professor | 11 | 5% |
Other | 32 | 14% |
Unknown | 25 | 11% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 92 | 41% |
Biochemistry, Genetics and Molecular Biology | 33 | 15% |
Engineering | 17 | 8% |
Computer Science | 11 | 5% |
Environmental Science | 8 | 4% |
Other | 21 | 9% |
Unknown | 41 | 18% |