Title |
The Fox/Forkhead transcription factor family of the hemichordate Saccoglossus kowalevskii
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Published in |
EvoDevo, May 2014
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DOI | 10.1186/2041-9139-5-17 |
Pubmed ID | |
Authors |
Jens H Fritzenwanker, John Gerhart, Robert M Freeman, Christopher J Lowe |
Abstract |
The Fox gene family is a large family of transcription factors that arose early in organismal evolution dating back to at least the common ancestor of metazoans and fungi. They are key components of many gene regulatory networks essential for embryonic development. Although much is known about the role of Fox genes during vertebrate development, comprehensive comparative studies outside vertebrates are sparse. We have characterized the Fox transcription factor gene family from the genome of the enteropneust hemichordate Saccoglossus kowalevskii, including phylogenetic analysis, genomic organization, and expression analysis during early development. Hemichordates are a sister group to echinoderms, closely related to chordates and are a key group for tracing the evolution of gene regulatory mechanisms likely to have been important in the diversification of the deuterostome phyla. |
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Mendeley readers
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Researcher | 15 | 22% |
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Immunology and Microbiology | 1 | 1% |
Other | 3 | 4% |
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