Title |
The effectiveness of antioxidant vitamins C and E in reducing myocardial infarct size in patients subjected to percutaneous coronary angioplasty (PREVEC Trial): study protocol for a pilot randomized double-blind controlled trial
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Published in |
Trials, May 2014
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DOI | 10.1186/1745-6215-15-192 |
Pubmed ID | |
Authors |
Ramón Rodrigo, Daniel Hasson, Juan C Prieto, Gastón Dussaillant, Cristóbal Ramos, Lucio León, Javier Gárate, Nicolás Valls, Juan G Gormaz |
Abstract |
Acute myocardial infarction (AMI) is the leading cause of mortality worldwide. Oxidative stress has been involved in the ischemia-reperfusion injury in AMI. It has been suggested that reperfusion accounts for up to 50% of the final size of a myocardial infarct, a part of the damage likely to be prevented.Therefore, we propose that antioxidant reinforcement through vitamins C and E supplementation should protect against the ischemia-reperfusion damage, thus decreasing infarct size.The PREVEC Trial (Prevention of reperfusion damage associated with percutaneous coronary angioplasty following acute myocardial infarction) seeks to evaluate whether antioxidant vitamins C and E reduce infarct size in patients subjected to percutaneous coronary angioplasty after AMI. |
X Demographics
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Chile | 1 | 1% |
Australia | 1 | 1% |
Unknown | 88 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 14 | 16% |
Student > Bachelor | 13 | 14% |
Researcher | 10 | 11% |
Student > Ph. D. Student | 7 | 8% |
Student > Postgraduate | 6 | 7% |
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Economics, Econometrics and Finance | 3 | 3% |
Other | 10 | 11% |
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