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Transcriptomic evidence for immaturity of the prefrontal cortex in patients with schizophrenia

Overview of attention for article published in Molecular Brain, May 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • High Attention Score compared to outputs of the same age and source (94th percentile)

Mentioned by

blogs
1 blog
twitter
11 X users
googleplus
1 Google+ user

Citations

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43 Dimensions

Readers on

mendeley
74 Mendeley
citeulike
1 CiteULike
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Title
Transcriptomic evidence for immaturity of the prefrontal cortex in patients with schizophrenia
Published in
Molecular Brain, May 2014
DOI 10.1186/1756-6606-7-41
Pubmed ID
Authors

Hideo Hagihara, Koji Ohira, Keizo Takao, Tsuyoshi Miyakawa

Abstract

Schizophrenia, a severe psychiatric disorder, has a lifetime prevalence of 1%. The exact mechanisms underlying this disorder remain unknown, though theories abound. Recent studies suggest that particular cell types and biological processes in the schizophrenic cortex have a pseudo-immature status in which the molecular properties partially resemble those in the normal immature brain. However, genome-wide gene expression patterns in the brains of patients with schizophrenia and those of normal infants have not been directly compared. Here, we show that the gene expression patterns in the schizophrenic prefrontal cortex (PFC) resemble those in the juvenile PFC.

X Demographics

X Demographics

The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 74 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 1%
Chile 1 1%
Canada 1 1%
Unknown 71 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 15 20%
Student > Ph. D. Student 13 18%
Student > Master 11 15%
Student > Doctoral Student 7 9%
Student > Bachelor 6 8%
Other 11 15%
Unknown 11 15%
Readers by discipline Count As %
Neuroscience 20 27%
Medicine and Dentistry 12 16%
Psychology 11 15%
Agricultural and Biological Sciences 10 14%
Biochemistry, Genetics and Molecular Biology 5 7%
Other 3 4%
Unknown 13 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 March 2017.
All research outputs
#1,918,056
of 22,756,196 outputs
Outputs from Molecular Brain
#56
of 1,106 outputs
Outputs of similar age
#20,470
of 226,522 outputs
Outputs of similar age from Molecular Brain
#1
of 17 outputs
Altmetric has tracked 22,756,196 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,106 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,522 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.