Title |
Genome-wide identification of Hfq-regulated small RNAs in the fire blight pathogen Erwinia amylovora discovered small RNAs with virulence regulatory function
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Published in |
BMC Genomics, May 2014
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DOI | 10.1186/1471-2164-15-414 |
Pubmed ID | |
Authors |
Quan Zeng, George W Sundin |
Abstract |
Erwinia amylovora is a phytopathogenic bacterium and causal agent of fire blight disease in apples and pears. Although many virulence factors have been characterized, the coordination of expression of these virulence factors in E. amylovora is still not clear. Regulatory small RNAs (sRNAs) are important post-transcriptional regulatory components in bacteria. A large number of sRNAs require the RNA chaperone Hfq for both stability and functional activation. In E. amylovora, Hfq was identified as a major regulator of virulence and various virulence traits. However, information is still lacking about Hfq-dependent sRNAs on a genome scale, including the virulence regulatory functions of these sRNAs in E. amylovora. |
X Demographics
Geographical breakdown
Country | Count | As % |
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France | 1 | 20% |
Unknown | 4 | 80% |
Demographic breakdown
Type | Count | As % |
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Scientists | 2 | 40% |
Members of the public | 2 | 40% |
Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Tunisia | 1 | 2% |
Unknown | 55 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 13 | 23% |
Researcher | 9 | 16% |
Student > Master | 9 | 16% |
Student > Bachelor | 6 | 11% |
Student > Postgraduate | 3 | 5% |
Other | 6 | 11% |
Unknown | 10 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 25 | 45% |
Biochemistry, Genetics and Molecular Biology | 9 | 16% |
Nursing and Health Professions | 2 | 4% |
Environmental Science | 2 | 4% |
Immunology and Microbiology | 2 | 4% |
Other | 4 | 7% |
Unknown | 12 | 21% |