Title |
Ex vivo anti-malarial drugs sensitivity profile of Plasmodium falciparum field isolates from Burkina Faso five years after the national policy change
|
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Published in |
Malaria Journal, May 2014
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DOI | 10.1186/1475-2875-13-207 |
Pubmed ID | |
Authors |
Halidou Tinto, Léa N Bonkian, Louis A Nana, Isidore Yerbanga, Moussa Lingani, Adama Kazienga, Innocent Valéa, Hermann Sorgho, Hervé Kpoda, Tinga Robert Guiguemdé, Jean Bosco Ouédraogo, Petronella F Mens, Henk Schallig, Umberto D’Alessandro |
Abstract |
The recent reports on the decreasing susceptibility of Plasmodium falciparum to artemisinin derivatives along the Thailand and Myanmar border are worrying. Indeed it may spread to India and then Africa, repeating the same pattern observed for chloroquine resistance. Therefore, it is essential to start monitoring P. falciparum sensitivity to artemisinin derivatives and its partner drugs in Africa. Efficacy of AL and ASAQ were tested by carrying out an in vivo drug efficacy test, with an ex vivo study against six anti-malarial drugs nested into it. Results of the latter are reported here. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Burkina Faso | 2 | 2% |
United Kingdom | 1 | 1% |
France | 1 | 1% |
Belgium | 1 | 1% |
Unknown | 84 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 22 | 25% |
Researcher | 13 | 15% |
Student > Master | 10 | 11% |
Professor > Associate Professor | 5 | 6% |
Student > Bachelor | 5 | 6% |
Other | 15 | 17% |
Unknown | 19 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 21 | 24% |
Agricultural and Biological Sciences | 14 | 16% |
Biochemistry, Genetics and Molecular Biology | 13 | 15% |
Social Sciences | 4 | 4% |
Nursing and Health Professions | 3 | 3% |
Other | 11 | 12% |
Unknown | 23 | 26% |