Title |
Outcome of artemether-lumefantrine treatment for uncomplicated malaria in HIV-infected adult patients on anti-retroviral therapy
|
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Published in |
Malaria Journal, May 2014
|
DOI | 10.1186/1475-2875-13-205 |
Pubmed ID | |
Authors |
Betty A Maganda, Omary MS Minzi, Appolinary AR Kamuhabwa, Billy Ngasala, Philip G Sasi |
Abstract |
Malaria and HIV infections are both highly prevalent in sub-Saharan Africa, with HIV-infected patients being at higher risks of acquiring malaria. The majority of antiretroviral (ART) and anti-malarial drugs are metabolized by the CYP450 system, creating a chance of drug-drug interaction upon co-administration. Limited data are available on the effectiveness of the artemether-lumefantrine combination (AL) when co-administered with non-nucleoside reverse transcriptase inhibitors (NNRTIs). The aim of this study was to compare anti-malarial treatment responses between HIV-1 infected patients on either nevirapine- or efavirenz-based treatment and those not yet on ART (control-arm) with uncomplicated falciparum malaria, treated with AL. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 2% |
Tanzania, United Republic of | 1 | 2% |
Unknown | 53 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 13 | 24% |
Researcher | 12 | 22% |
Student > Ph. D. Student | 7 | 13% |
Student > Bachelor | 6 | 11% |
Student > Doctoral Student | 5 | 9% |
Other | 5 | 9% |
Unknown | 7 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 23 | 42% |
Pharmacology, Toxicology and Pharmaceutical Science | 5 | 9% |
Immunology and Microbiology | 4 | 7% |
Social Sciences | 3 | 5% |
Business, Management and Accounting | 2 | 4% |
Other | 9 | 16% |
Unknown | 9 | 16% |