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Adverse outcomes associated with opioid prescription for acute low back pain: a systematic review protocol

Overview of attention for article published in Systematic Reviews, August 2017
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Title
Adverse outcomes associated with opioid prescription for acute low back pain: a systematic review protocol
Published in
Systematic Reviews, August 2017
DOI 10.1186/s13643-017-0556-x
Pubmed ID
Authors

Natalia Mouravska, Laura Zielinski, Meha Bhatt, Nitika Sanger, Monica Bawor, Brittany Dennis, Laura Banfield, James MacKillop, James Paul, Andrew Worster, Philip Laplante, Lehana Thabane, Zainab Samaan

Abstract

Acute low back pain (ALBP) is the top cause of global disability, demonstrating a significant impact on individuals and society and demanding the need for appropriate management. There is a trend towards an increasing number of opioid prescriptions for ALBP despite the lack of investigation for its various short- and long-term outcomes. The objective of this review is to examine adverse outcomes associated with opioid use for ALBP. Using a search strategy, the search will be conducted using the following electronic databases: PubMed/MEDLINE, EMBASE, PsycINFO, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Web of Science, Cochrane Library, the National Institutes for Health Clinical Trials Registry and the World Health Organization International Clinical Trials Registry Platform (WHO ICTRP). We will include randomized clinical trials and observational studies investigating the impact of opioid use in ALBP in the adult population. All phases of screening, data extraction and assessment of methodological quality will be performed by two independent reviewers. We will perform quality and risk of bias assessment for the included articles and compare high and low risk of bias with a sensitivity analysis. We will conduct random- and fixed-effects meta-analyses with heterogeneity calculated using the I (2) statistic and evaluate publication bias. There are current guidelines published to alert clinicians in prescribing opioids for ALBP due to its likelihood of misuse, yet there is little change in prescribing patterns. To date, there is an absence of systematic information about the outcomes of prescription opioid in patients with ALBP. We will address this gap by providing evidence that will be useful for clinical practice. PROSPERO CRD42016033090.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 63 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 11 17%
Researcher 7 11%
Student > Bachelor 6 10%
Student > Doctoral Student 5 8%
Student > Ph. D. Student 4 6%
Other 10 16%
Unknown 20 32%
Readers by discipline Count As %
Medicine and Dentistry 15 24%
Nursing and Health Professions 8 13%
Biochemistry, Genetics and Molecular Biology 3 5%
Social Sciences 3 5%
Psychology 2 3%
Other 8 13%
Unknown 24 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 June 2018.
All research outputs
#20,442,790
of 22,997,544 outputs
Outputs from Systematic Reviews
#1,920
of 2,005 outputs
Outputs of similar age
#277,277
of 317,683 outputs
Outputs of similar age from Systematic Reviews
#54
of 58 outputs
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We're also able to compare this research output to 58 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.