Title |
Clinical features of childhood granulomatosis with polyangiitis (wegener’s granulomatosis)
|
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Published in |
Pediatric Rheumatology, May 2014
|
DOI | 10.1186/1546-0096-12-18 |
Pubmed ID | |
Authors |
Marek Bohm, Maria Isabel Gonzalez Fernandez, Seza Ozen, Angela Pistorio, Pavla Dolezalova, Paul Brogan, Giancarlo Barbano, Claudia Sengler, Marisa Klein-Gitelman, Pierre Quartier, Anders Fasth, Troels Herlin, Maria Teresa R A Terreri, Susan Nielsen, Marion A J van Rossum, Tadej Avcin, Esteban Rodolfo Castell, Ivan Foeldvari, Dirk Foell, Anuela Kondi, Isabelle Koné-Paut, Rolf-Michael Kuester, Hartmut Michels, Nico Wulffraat, Halima Ben Amer, Clara Malattia, Alberto Martini, Nicolino Ruperto, the Paediatric Rheumatology International Trials Organisation (PRINTO) |
Abstract |
Granulomatosis with polyangiitis (GPA), formerly known as Wegener's granulomatosis (WG), belongs to the group of ANCA-associated necrotizing vasculitides. This study describes the clinical picture of the disease in a large cohort of GPA paediatric patients. Children with age at diagnosis ≤ 18 years, fulfilling the EULAR/PRINTO/PRES GPA/WG classification criteria were extracted from the PRINTO vasculitis database. The clinical signs/symptoms and laboratory features were analysed before or at the time of diagnosis and at least 3 months thereafter and compared with other paediatric and adult case series (>50 patients) derived from the literature. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 87 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 12 | 14% |
Student > Ph. D. Student | 12 | 14% |
Researcher | 10 | 11% |
Student > Master | 10 | 11% |
Professor | 5 | 6% |
Other | 22 | 25% |
Unknown | 16 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 53 | 61% |
Biochemistry, Genetics and Molecular Biology | 3 | 3% |
Business, Management and Accounting | 2 | 2% |
Agricultural and Biological Sciences | 1 | 1% |
Computer Science | 1 | 1% |
Other | 9 | 10% |
Unknown | 18 | 21% |