Title |
Multiple transcription factors directly regulate Hox gene lin-39 expression in ventral hypodermal cells of the C. elegans embryo and larva, including the hypodermal fate regulators LIN-26 and ELT-6
|
---|---|
Published in |
BMC Developmental Biology, May 2014
|
DOI | 10.1186/1471-213x-14-17 |
Pubmed ID | |
Authors |
Wan-Ju Liu, John S Reece-Hoyes, Albertha JM Walhout, David M Eisenmann |
Abstract |
Hox genes encode master regulators of regional fate specification during early metazoan development. Much is known about the initiation and regulation of Hox gene expression in Drosophila and vertebrates, but less is known in the non-arthropod invertebrate model system, C. elegans. The C. elegans Hox gene lin-39 is required for correct fate specification in the midbody region, including the Vulval Precursor Cells (VPCs). To better understand lin-39 regulation and function, we aimed to identify transcription factors necessary for lin-39 expression in the VPCs, and in particular sought factors that initiate lin-39 expression in the embryo. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 3 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 67% |
Scientists | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Netherlands | 1 | 5% |
United States | 1 | 5% |
Czechia | 1 | 5% |
Unknown | 17 | 85% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 7 | 35% |
Researcher | 4 | 20% |
Student > Ph. D. Student | 3 | 15% |
Student > Doctoral Student | 2 | 10% |
Student > Master | 2 | 10% |
Other | 1 | 5% |
Unknown | 1 | 5% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 8 | 40% |
Agricultural and Biological Sciences | 7 | 35% |
Medicine and Dentistry | 2 | 10% |
Veterinary Science and Veterinary Medicine | 1 | 5% |
Environmental Science | 1 | 5% |
Other | 0 | 0% |
Unknown | 1 | 5% |