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Evaluating the optimal timing of surgical antimicrobial prophylaxis: study protocol for a randomized controlled trial

Overview of attention for article published in Trials, May 2014
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Title
Evaluating the optimal timing of surgical antimicrobial prophylaxis: study protocol for a randomized controlled trial
Published in
Trials, May 2014
DOI 10.1186/1745-6215-15-188
Pubmed ID
Authors

Edin Mujagic, Tibor Zwimpfer, Walter R Marti, Marcel Zwahlen, Henry Hoffmann, Christoph Kindler, Christoph Fux, Heidi Misteli, Lukas Iselin, Andrea Kopp Lugli, Christian A Nebiker, Urs von Holzen, Fabrizio Vinzens, Marco von Strauss, Stefan Reck, Marko Kraljević, Andreas F Widmer, Daniel Oertli, Rachel Rosenthal, Walter P Weber

Abstract

Surgical site infections are the most common hospital-acquired infections among surgical patients. The administration of surgical antimicrobial prophylaxis reduces the risk of surgical site infections . The optimal timing of this procedure is still a matter of debate. While most studies suggest that it should be given as close to the incision time as possible, others conclude that this may be too late for optimal prevention of surgical site infections. A large observational study suggests that surgical antimicrobial prophylaxis should be administered 74 to 30 minutes before surgery. The aim of this article is to report the design and protocol of a randomized controlled trial investigating the optimal timing of surgical antimicrobial prophylaxis.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 110 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 <1%
Unknown 109 99%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 15 14%
Student > Master 15 14%
Researcher 11 10%
Other 9 8%
Student > Bachelor 9 8%
Other 26 24%
Unknown 25 23%
Readers by discipline Count As %
Medicine and Dentistry 46 42%
Pharmacology, Toxicology and Pharmaceutical Science 9 8%
Nursing and Health Professions 9 8%
Unspecified 3 3%
Business, Management and Accounting 2 2%
Other 10 9%
Unknown 31 28%