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Identification of G protein-coupled receptors in Schistosoma haematobium and S. mansoni by comparative genomics

Overview of attention for article published in Parasites & Vectors, May 2014
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Title
Identification of G protein-coupled receptors in Schistosoma haematobium and S. mansoni by comparative genomics
Published in
Parasites & Vectors, May 2014
DOI 10.1186/1756-3305-7-242
Pubmed ID
Authors

Tulio D L Campos, Neil D Young, Pasi K Korhonen, Ross S Hall, Stefano Mangiola, Andrew Lonie, Robin B Gasser

Abstract

Schistosomiasis is a parasitic disease affecting ~200 million people worldwide. Schistosoma haematobium and S. mansoni are two relatively closely related schistosomes (blood flukes), and the causative agents of urogenital and hepatointestinal schistosomiasis, respectively. The availability of genomic, transcriptomic and proteomic data sets for these two schistosomes now provides unprecedented opportunities to explore their biology, host interactions and schistosomiasis at the molecular level. A particularly important group of molecules involved in a range of biological and developmental processes in schistosomes and other parasites are the G protein-coupled receptors (GPCRs). Although GPCRs have been studied in schistosomes, there has been no detailed comparison of these receptors between closely related species. Here, using a genomic-bioinformatic approach, we identified and characterised key GPCRs in S. haematobium and S. mansoni (two closely related species of schistosome).

X Demographics

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 2%
Canada 1 2%
Australia 1 2%
Brazil 1 2%
Unknown 52 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 27%
Researcher 9 16%
Student > Master 7 13%
Professor > Associate Professor 4 7%
Student > Bachelor 4 7%
Other 5 9%
Unknown 12 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 18 32%
Biochemistry, Genetics and Molecular Biology 10 18%
Pharmacology, Toxicology and Pharmaceutical Science 3 5%
Veterinary Science and Veterinary Medicine 3 5%
Environmental Science 1 2%
Other 3 5%
Unknown 18 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 February 2015.
All research outputs
#14,781,203
of 22,756,196 outputs
Outputs from Parasites & Vectors
#3,072
of 5,452 outputs
Outputs of similar age
#126,697
of 226,570 outputs
Outputs of similar age from Parasites & Vectors
#17
of 40 outputs
Altmetric has tracked 22,756,196 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,452 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 38th percentile – i.e., 38% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,570 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 40 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.