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Improved delivery of the OVA-CD4 peptide to T helper cells by polymeric surface display on Salmonella

Overview of attention for article published in Microbial Cell Factories, June 2014
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1 X user

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Title
Improved delivery of the OVA-CD4 peptide to T helper cells by polymeric surface display on Salmonella
Published in
Microbial Cell Factories, June 2014
DOI 10.1186/1475-2859-13-80
Pubmed ID
Authors

Junjie Zhang, Leon De Masi, Beena John, Wenxin Chen, Dieter M Schifferli

Abstract

Autotransporter proteins represent a treasure trove for molecular engineers who modify Gram-negative bacteria for the export or secretion of foreign proteins across two membrane barriers. A particularly promising direction is the development of autotransporters as antigen display or secretion systems. Immunologists have been using ovalbumin as a reporter antigen for years and have developed sophisticated tools to detect specific T cells that respond to ovalbumin. Although ovalbumin-expressing bacteria are being used to trace T cell responses to colonizing or invading pathogens, current constructs for ovalbumin presentation have not been optimized.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 21 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 19%
Student > Master 3 14%
Student > Bachelor 3 14%
Researcher 2 10%
Student > Doctoral Student 1 5%
Other 1 5%
Unknown 7 33%
Readers by discipline Count As %
Agricultural and Biological Sciences 4 19%
Immunology and Microbiology 4 19%
Biochemistry, Genetics and Molecular Biology 3 14%
Pharmacology, Toxicology and Pharmaceutical Science 1 5%
Medicine and Dentistry 1 5%
Other 0 0%
Unknown 8 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 June 2014.
All research outputs
#18,373,576
of 22,757,090 outputs
Outputs from Microbial Cell Factories
#1,196
of 1,592 outputs
Outputs of similar age
#163,913
of 228,065 outputs
Outputs of similar age from Microbial Cell Factories
#13
of 17 outputs
Altmetric has tracked 22,757,090 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,592 research outputs from this source. They receive a mean Attention Score of 4.4. This one is in the 14th percentile – i.e., 14% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 228,065 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.